Journal of hazardous materials, 161(1), 325-329 (2008-05-09)
A novel and sensitive spectrophotometric method for the determination of molybdenum at trace levels in environmental and biological samples is proposed. The method is based on the reaction of Mo (V) with thiocyanate (SCN(-)) and methyltrioctyl ammonium chloride (MTOAC) in
To obtain a separation of the epidermal and dermal compartments to examine compartment specific biological mechanisms in the skin, we incubated 4 mm human skin punch biopsies in ammonium thiocyanate. We wanted to test (i) the histological quality of the
The Journal of investigative dermatology, 135(8), 2077-2083 (2015-04-02)
Epigenetic modifications by DNA methylation are associated with a wide range of diseases. Previous studies in psoriasis have concentrated on epigenetic changes in immune cells or in total skin biopsies that include stromal-associated changes. In order to improve our understanding
Journal of immunological methods, 387(1-2), 36-42 (2012-10-02)
Antibody avidity, defined as the strength of binding between antibody and antigen, represents a functional measure of affinity maturation of antibodies. Determination of the antibody avidity is usually performed separating high and low avidity antibodies by dissociating agents, but measurement
As global transcriptome analyses with a growing demand on layer-specific applications are widely used in cutaneous biology, we investigated the effect of established and optimized dermo-epidermal separation methods on the quality of RNA. We compared enzymatic separation with dispase, chemical
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
