1642358

Sunitinib malate

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, SU 011248, SU 11248, SU112248
• Fórmula empírica (notación de Hill): C₂₂H₂₇FN₄O₂ · C₄H₆O₅
• Número de CAS: 341031-54-7
• Peso molecular: 532.56
• Número MDL: MFCD08282795
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• Agency: USP
• familia API: sunitinib
• envase: pkg of 200 mg
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical
• formato: neat
• cadena SMILES: O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
• InChI: 1S/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7)(H,8,9)/b17-12-;/t;2-/m.0/s1
• Clave InChI: LBWFXVZLPYTWQI-IPOVEDGCSA-N

Descripción

Descripción general

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Aplicación

Sunitinib malate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Acciones bioquímicas o fisiológicas

Sunitinib malate is a receptor tyrosine kinase inhibitor, which targets VEGF-R1, VEGF-R2, VEGF-R3, PDGF-Rα, PDGF-Rβ, KIT, FLT3, CSF-1R, and RET. Sunitinib malate is an anticancer drug.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360,H372
• Consejos de prudencia: P202 - P260 - P264 - P280 - P308 + P313 - P405
• Clasificaciones de peligro: Repr. 1B - STOT RE 1 Oral
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable