1604880

Rizatriptan benzoate

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Rizatriptan benzoate salt, MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
• Fórmula empírica (notación de Hill): C₁₅H₁₉N₅ · C₇H₆O₂
• Número CAS: 145202-66-0
• Peso molecular: 391.47
• NACRES: NA.24
• PubChem Substance ID: 329751055
• UNSPSC Code: 41116107
• MDL number: MFCD00866224

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: rizatriptan
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23
• InChI: 1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)
• InChI key: JPRXYLQNJJVCMZ-UHFFFAOYSA-N
• Gene Information: human ... HTR1B(3351), HTR1D(3352)

Descripción

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rizatriptan benzoate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Rizatriptan Benzoate Orally Disintegrating Tablets
• Rizatriptan Benzoate Tablets

Biochem/physiol Actions

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H360
• pcodes: P201 - P280 - P308 + P313
• Hazard Classifications: Repr. 1B
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable