1372050

Lysophosphatidylcholine

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: L-α-Lysophosphatidylcholine from egg yolk, 1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
• Número de CAS: 9008-30-4
• Número MDL: MFCD00131444
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: lysophosphatidylcholine
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: −20°C

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Lysophosphatidylcholine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Egg Phospholipids

Acciones bioquímicas o fisiológicas

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na⁺ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K⁺ channels.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable