T3309
Transferrina human
≥98%
Sinónimos:
Siderofilina parcialmente saturada
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About This Item
Productos recomendados
origen biológico
human
Nivel de calidad
Análisis
≥98%
formulario
powder
contenido de hierro
300-600 ppm
técnicas
cell culture | stem cell: suitable
impurezas
≤1.0 EU/mg endotoxin
Nº de acceso UniProt
temp. de almacenamiento
2-8°C
Información sobre el gen
human ... TF(7018)
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Descripción general
Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes.
Aplicación
Transferrin has been used:
- in isolation of epidermal stem cells and cell expansion
- to study the effect of compound treatment on transferrin uptake
- for transferrin uptake and confocal imaging
Acciones bioquímicas o fisiológicas
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance.
Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present.
Nota de análisis
Pureza por electroforesis en agarosa.
Cláusula de descargo de responsabilidad
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Los clientes también vieron
British journal of haematology, 80(2), 235-241 (1992-02-01)
The effect of different forms of iron and iron-binding proteins on the proliferative response of human lymphocytes to phytohaemagglutinin (PHA) has been studied. Transferrin enhanced proliferation, the effect being proportional to the degree of iron saturation up to 100%, but
Non-invasive in vivo imaging of near infrared-labeled transferrin in breast cancer cells and tumors using fluorescence lifetime FRET
PLoS ONE, 8(11), e80269-e80269 (2013)
Bioengineering strategies for designing targeted cancer therapies
Advances in Cancer Research, 118(11), 1-59 (2013)
Nutritional issues in the patient with diabetes and foot ulcers
Levin and O'Neal's The Diabetic Foot, 199-217 (2008)
Severe hypochromic microcytic anemia in a patient with congenital atransferrinemia
Pediatric Hematology and Oncology, 26(5), 356-362 (2009)
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