T0632

Sodium thioglycolate

≥96.5% (iodometric)

• Sinónimos: Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt
• Fórmula lineal: HSCH₂COONa
• Número CAS: 367-51-1
• Peso molecular: 114.10
• UNSPSC Code: 12352201
• NACRES: NA.25
• PubChem Substance ID: 24899901
• EC Number: 206-696-4
• Beilstein/REAXYS Number: 4569109
• MDL number: MFCD00043386

Propiedades

• Quality Segment: 200
• assay: ≥96.5% (iodometric)
• form: powder
• color: white to off-white
• useful pH range: 6.7 (20 °C, 100 g/L)
• mp: >300 °C (lit.)
• solubility: water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
• storage temp.: −20°C
• SMILES string: [Na+].[O-]C(=O)CS
• InChI: 1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
• InChI key: GNBVPFITFYNRCN-UHFFFAOYSA-M

Descripción

Application

Sodium thioglycolate has been used:

• as a growth supplement in enrichment media and to study its effect on Arcobacter
• in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
• in electron microscopy

Biochem/physiol Actions

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Disclaimer

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Información de seguridad

• Pictogramas: GHS06,GHS05
• Palabra de advertencia: Danger
• Códigos de peligro: H290,H301,H312,H317,H412
• Indicaciones de precaución: P234 - P261 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• EPI (equipos de protección individual): dust mask type N95 (US), Eyeshields, Gloves