SRP8008

FTO mouse

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• Sinónimos: EC 1.14.11, FATSO, Fat mass and obesity-associated protein, Preadipocyte factor 1
• Código UNSPSC: 12352200
• NACRES: NA.32

Propiedades

• origen biológico: mouse
• recombinante: expressed in E. coli
• etiqueta: His tagged
• Ensayo: >90% (SDS-PAGE)
• Formulario: liquid
• mol peso: ~55 kDa by SDS-PAGE
• envase: pkg of 10 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• concentración: ≥0.2 mg/mL
• impurezas: <1 EU/μg endotoxin, tested
• color: clear
• Nº de acceso UniProt: Q8BGW1
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: mouse ... Fto(26383)

Descripción

Descripción general

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Forma física

Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.

Otras notas

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable