SRP4688
Prolactin from mouse
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
Sinónimos:
Luterotropic hormone, Lutetropin, Mammotropin, PRL
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Código UNSPSC:
12352200
NACRES:
NA.32
Productos recomendados
origen biológico
mouse
recombinante
expressed in E. coli
Análisis
≥95% (HPLC)
≥95% (SDS-PAGE)
formulario
lyophilized
mol peso
~22.5 kDa
envase
pkg of 50 μg
condiciones de almacenamiento
avoid repeated freeze/thaw cycles
técnicas
cell culture | mammalian: suitable
impurezas
endotoxin, tested
Nº de acceso NCBI
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
mouse ... Prl(256249)
Descripción general
Prolactin (PRL, also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. It belongs to the cytokine receptor superfamily. Recombinant mouse prolactin is a 22.5kDa globular protein containing 198 amino acid residues.
Aplicación
PRL (Prolactin) from mouse has been used to study the effects of prolactin on the length, motility and viability of larvae of Toxocara canis.
Prolactin from mouse has been used as a supplement in mammary epithelial basal medium (MEBM) for mammary epithelial cell culture.
Acciones bioquímicas o fisiológicas
PRL (Prolactin) primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. In mice, prolactin also prevents hepatocellular carcinoma by suppressing MAP3K (mitogen-activated protein kinase kinase kinase)-dependent activation of c-myc.
Prolactin synthesis is regulated in the hypothalamus. Dopamine and prolactin secretion from anterior pituitary lactotrophs are controlled by a negative feedback loop. Prolactin modulates xenobiotic metabolism by controlling the mRNA expression cytochrome p450 enzymes.
Forma física
Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 8.0 plus 50 mM NaCl.
Reconstitución
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
L E Chávez-Güitrón et al.
Experimental parasitology, 198, 1-6 (2019-01-12)
The in vitro effect of progesterone in T. canis larvae on their enlargement and motility were evaluated, together to the possible presence of progesterone receptors (PRs). T. canis larvae were cultured in RPMI-1640 with different concentrations of progesterone (0, 20
Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like disease.
Legorreta-Haquet MV
Clinical & Developmental Immunology, doi: 10- doi: 10 (2013)
Chromosome segregation fidelity in epithelia requires tissue architecture
Knouse KA, et al.
Cell, 175(1), 200-211 (2018)
Hui Li et al.
American journal of physiology. Gastrointestinal and liver physiology, 320(2), G183-G192 (2020-11-19)
Gastric vagal afferents (GVAs) sense food-related mechanical stimuli and signal to the central nervous system, to integrate control of meal termination. Pregnancy is characterized by increased maternal food intake, which is essential for normal fetal growth and to maximize progeny
Prolactin stimulation of ornithine decarboxylase activity in the mammary gland may involve an activation of protein kinase C.
Rillema JA
Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine, 178, 490-490 (1095)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico