SML3158

6-Methylflavone

≥98% (HPLC)

• Sinónimos: 6-Methyl-2-phenyl-4H-1-benzopyran-4-one, 6-Methyl-2-phenyl-4H-chromen-4-one
• Fórmula empírica (notación de Hill): C₁₆H₁₂O₂
• Número CAS: 29976-75-8
• Peso molecular: 236.27
• UNSPSC Code: 51111800
• NACRES: NA.77
• MDL number: MFCD00017461
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• mp: 119-122 °C (dec.) (lit.)
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3
• InChI: 1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
• InChI key: NOQJBXPAMJLUSS-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable