SML2670

BAY-8002

≥98% (HPLC)

• Sinónimos: 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid, 2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]-benzoic acid
• Fórmula empírica (notación de Hill): C₂₀H₁₄ClNO₅S
• Número CAS: 724440-27-1
• Peso molecular: 415.85
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD05157149
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [S](=O)(=O)(c2cc(c(cc2)Cl)C(=O)Nc3c(cccc3)C(=O)O)c1ccccc1
• InChI: 1S/C20H14ClNO5S/c21-17-11-10-14(28(26,27)13-6-2-1-3-7-13)12-16(17)19(23)22-18-9-5-4-8-15(18)20(24)25/h1-12H,(H,22,23)(H,24,25)
• InChI key: CLAUJSRBKSRTGQ-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

BAY-8002 is an orally available, potent and selective inhibitor of lactate transporter MCT1 (monocarboxylate transporter 1; SLC16A1) that potently inhibits bidirectional lactate transport. BAY-8002 exhibits antiproliferative activity in numerous cancer cell lines. BAY-8002 induces accumulation of lactate and significantly inhibits tumor growth in mice model. It does not cause tumor regression.

orally available, potent and selective inhibitor of lactate transporter MCT1

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable