SML2616

Bepotastine besilate

≥98% (HPLC), H1-receptor antagonist, powder

• Sinónimos: Bepreve, (+)-4-[[(S)-p-chloro-alpha-2­pyridylbenzyl]oxy]-1-piperidine butyric acid monobenzenesulfonate
• Fórmula empírica (notación de Hill): C₂₁H₂₅ClN₂O₃ · C₆H₆O₃S
• Número CAS: 190786-44-8
• Peso molecular: 547.06
• UNSPSC Code: 51111800
• NACRES: NA.77
• MDL number: MFCD01938491
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Nombre del producto: Bepotastine besilate, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D 4.5 to 6.5°, c = 1 in methanol
• storage condition: desiccated
• color: white to beige
• storage temp.: −20°C
• SMILES string: [S](=O)(=O)(O)c4ccccc4.Clc1ccc(cc1)[C@@H](OC3CCN(CC3)CCCC(=O)O)c2ncccc2
• InChI: 1S/C21H25ClN2O3.C6H6O3S/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26;7-10(8,9)6-4-2-1-3-5-6/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26);1-5H,(H,7,8,9)/t21-;/m1./s1
• InChI key: UDGHXQPQKQPSBB-ZMBIFBSDSA-N

Descripción

Biochem/physiol Actions

Bepotastine besilate is a second generation antihistamine used clinically for the treatment of itching associated with allergic conjunctivitis, allergic rhinitis and urticaria/pruritus. It is a direct H1-receptor antagonist that inhibits the release of histamine from mast cells.

Second generation antihistamine, H1-receptor antagonist

Información de seguridad

• Pictogramas: GHS08
• Palabra de advertencia: Warning
• Códigos de peligro: H361d
• Indicaciones de precaución: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable