SML2370

Dabigatran

≥95% (HPLC), Nonpeptide direct thrombin inhibitor, powder

• Sinónimos: BIBR-953, N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
• Fórmula empírica (notación de Hill): C₂₅H₂₅N₇O₃
• Número CAS: 211914-51-1
• Peso molecular: 471.51
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD09837830
• Assay: ≥95% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: Dabigatran, ≥95% (HPLC)
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: 0.1 M HCl: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N=C(N)C(C=C1)=CC=C1NCC(N2C)=NC3=C2C=CC(C(N(CCC(O)=O)C4=NC=CC=C4)=O)=C3
• InChI: 1S/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)
• InChI key: YBSJFWOBGCMAKL-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Dabigatran is a nonpeptide direct thrombin inhibitor. It is an anticoagulant that functions by directly inhibiting both free and fibrin-bound thrombin. Dabigatron has been shown to prevent strokes in those with atrial fibrillation not caused by heart valve issues.

Nonpeptide, direct thrombin inhibitor

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable