SML2286

BIIL260 hydrochloride

≥98% (HPLC)

• Sinónimos: 4-(3-{4-[1-(4-Hydroxy-phenyl)-1-methyl-ethyl]-phenoxymethyl}-benzyloxy)-benzamidine hydrochloride, BIIL 260 hydrochloride, BIIL-260 hydrochloride
• Fórmula empírica (notación de Hill): C₃₀H₃₀N₂O₃ · xHCl
• Número CAS: 204974-93-6
• Peso molecular: 466.57 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N\C(=N/[H])\c1ccc(cc1)OCc2cc(ccc2)COc3ccc(cc3)C(C)(C)c4ccc(cc4)O
• InChI: 1S/C30H30N2O3/c1-30(2,24-8-12-26(33)13-9-24)25-10-16-28(17-11-25)35-20-22-5-3-4-21(18-22)19-34-27-14-6-23(7-15-27)29(31)32/h3-18,33H,19-20H2,1-2H3,(H3,31,32)
• InChI key: MBLJFKQACMILLC-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

BIIL260 is a selective and potent leukotriene B4 (BLT1) receptor antagonist with a Ki value of 1.8 nM in human U937 cells. BIIL260 was used found to act as an inverse agonist, stabilizing the inactive state of BLT1.

Leukotriene B4 (BLT1) receptor antagonist

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable