SML2193

Altenusin

≥98% (HPLC)

• Sinónimos: 3,4′,5′-Trihydroxy-5-methoxy-2′-methyl[1,1′-biphenyl]-2-carboxylic acid, Alutenusin
• Fórmula empírica (notación de Hill): C₁₅H₁₄O₆
• Número CAS: 31186-12-6
• Peso molecular: 290.27
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• biological source: Penicillium sp.
• assay: ≥98% (HPLC)
• form: powder
• color: yellow to orange
• storage temp.: −20°C
• SMILES string: OC1=CC(C2=CC(OC)=CC(O)=C2C(O)=O)=C(C)C=C1O
• InChI: 1S/C15H14O6/c1-8-5-13(16)14(17)7-11(8)12-6-9(20-2)3-4-10(12)15(18)21-19/h3-7,16-17,19H,1-2H3
• InChI key: GWGIZSANXIQQQR-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Altenusin, a non-steroidal fungal metabolite, is a potent and selective agonist of Farnesoid X receptor (FXR) that protects mice from high-fat diet induced obesity. Also it decreases blood glucose level, serum insulin level, and reduces lipid droplets accumulation. Altenusin inhibits trypanothione reductase from Trypanosoma cruzi.

potent and selective agonist of Farnesoid X receptor (FXR)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable