SML1869

Delafloxacin

≥98% (HPLC), fluoroquinolone antibiotic , powder

• Sinónimos: 1-(6-Amino-3,5-difluoro-2-pyridyl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-quinoline-3-carboxylic acid, ABT-492, WQ-3034
• Fórmula empírica (notación de Hill): C₁₈H₁₂ClF₃N₄O₄
• Número CAS: 189279-58-1
• Peso molecular: 440.76
• NACRES: NA.77
• UNSPSC Code: 51111800
• MDL number: MFCD09955301
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: Delafloxacin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: ClC1=C(N(C2=NC(N)=C(F)C=C2F)C=C(C(O)=O)C3=O)C3=CC(F)=C1N4CC(O)C4
• InChI: 1S/C18H12ClF3N4O4/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30)
• InChI key: DYDCPNMLZGFQTM-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Delafloxacin is a fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria such as MRSA.

Delafloxacin is a fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria such as MRSA. Delafloxacin targets both DNA gyrase and topoisomerase IV, inhibiting DNA synthesis. Unlike most fluoroquinolones, delafloxacin is weakly acidic, which increases its potency in an acidic environments such as those existing in inflammatory cells and in skin and soft tissue infections. Delafloxacin shows good activity against most fluoroquinolone-resistant strains.

Delafloxacin is mostly prefered for the treatment of respiratory tract infections.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable