SML1796

Atazanavir

≥98% (HPLC), HIV protease inhibitor, powder

• Sinónimos: 1,14-Dimethyl (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate, BMS-232632
• Fórmula empírica (notación de Hill): C₃₈H₅₂N₆O₇
• Número CAS: 198904-31-3
• Peso molecular: 704.86
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD08435966
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: Atazanavir, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -41 to -49°, c = 0.1 in ethanol
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C(N[C@@H](C(C)(C)C)C(N[C@H]([C@H](CN(CC1=CC=C(C2=NC=CC=C2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)O)CC3=CC=CC=C3)=O)OC
• InChI: 1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
• InChI key: AXRYRYVKAWYZBR-GASGPIRDSA-N

Descripción

General description

Atazanavir inhibits the cleavage of gag and gag-pol polyproteins in human immunodeficiency virus. It is absorbed and metabolized by cytochrome P450 present in the liver. It has minimal side effects and has no effect on insulin sensitivity and serum lipid profile.

Biochem/physiol Actions

Atazanavir is an antiviral HIV protease inhibitor.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• Clase de almacenamiento: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral