SML1238

Ertapenem sodium

≥90% (HPLC), powder, carbopenem antibiotic

• Sinónimos: (4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium, ZD-443 sodium
• Fórmula empírica (notación de Hill): C₂₂H₂₄N₃O₇S · Na
• Número CAS: 153773-82-1
• Peso molecular: 497.50
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥90% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Propiedades

• Nombre del producto: Ertapenem sodium, ≥90% (HPLC)
• Quality Segment: 100
• assay: ≥90% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• color: white to yellow
• storage temp.: room temp
• SMILES string: [Na+].S([C@@H]3CN[C@@H](C3)C(=O)Nc4cc(ccc4)C(=O)[O-])C1=C(N2[C@H]([C@H]1C)[C@H](C2=O)[C@H](O)C)C(=O)O
• InChI: 1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1
• InChI key: ZXNAQFZBWUNWJM-HRXMHBOMSA-M

Descripción

Application

Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.

Biochem/physiol Actions

Broad spectrum carbopenem antibiotic

Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.

Ertapenem sodium exhibits its activity against several aerobic and anaerobic microorganisms and is more resistant to β-lactamase enzymes. It has been studied in the treatment of several infectious diseases.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable