SML1101

Nedocromil sodium

≥98% (HPLC)

• Sinónimos: 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt, Nedocromil disodium salt
• Fórmula empírica (notación de Hill): C₁₉H₁₅NO₇ · 2 Na
• Número CAS: 69049-74-7
• Peso molecular: 415.30
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: , white to beige to brown
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].[n]1(c2c([c](cc1C(=O)[O-])=O)cc3c([o]c(c[c]3=O)C(=O)[O-])c2CCC)CC
• InChI: 1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
• InChI key: JQEKDNLKIVGXAU-UHFFFAOYSA-L

Descripción

Biochem/physiol Actions

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug.

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself.

Nedocromil is considered to be more effective in treating asthma compared to a placebo.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable