SML1073

BIX

≥98% (HPLC), molecular chaperone GRP78 inducer, powder

• Sinónimos: 2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid, BiP protein Inducer X
• Fórmula empírica (notación de Hill): C₉H₇NO₃S
• Número CAS: 101714-41-4
• Peso molecular: 209.22
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825455
• NACRES: NA.77
• MDL number: MFCD22415334
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: BIX, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC1=C(O)C=C(C(CSC#N)=O)C=C1
• InChI: 1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2
• InChI key: SVFLBLCWKKQKDW-UHFFFAOYSA-N

Descripción

Application

BIX has been used in cell viability assay.

Biochem/physiol Actions

BIX (BiP protein inducer X) induces the expression of the endoplasmic reticulum chaperone protein GRP78 (glucose regulated protein 78, BiP) leading to an attenuation of the unfolded protein response. BIX protects neuronal cells and retinal cells from ER-stress induced cell death.

BIX is an inducer of molecular chaperone GRP78 (BIP, Glucose regulated protein 78).

Other Notes

air sensitive

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• Clase de almacenamiento: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• hcodes: H302,H315,H317,H319
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1