SML1041

Atreleuton

≥98% (HPLC)

• Sinónimos: (R)-N-(3-(5-(4-Fluorophenylmethyl)thien-2-yl)-1-methyl-2-propynyl)-N-hydroxyurea, A8576, ABT 761, VIA-2291
• Fórmula empírica (notación de Hill): C₁₆H₁₅FN₂O₂S
• Número CAS: 154355-76-7
• Peso molecular: 318.37
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +40 to +50°, c = 1 in methanol
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Fc1ccc(cc1)Cc2[s]c(cc2)C#C[C@H](N(O)C(=O)N)C
• InChI: 1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1
• InChI key: MMSNEKOTSJRTRI-LLVKDONJSA-N

Descripción

Biochem/physiol Actions

Atreleuton is a reversible 5-lipoxygenase inhibitor.

Atreleuton is a reversible 5-lipoxygenase inhibitor. Atreleuton exhibits potent and selective inhibition of leukotriene formation both in vitro and in vivo.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable