The stability of this material in solution at 4°C has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months.
SML0545
CID 1067700
≥98% (HPLC)
Sinónimos:
2-(Benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid, 2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid, CID-1067700, CID1067700, SID57578339
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5 MG
128,00 €
25 MG
470,00 €
128,00 €
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5 MG
128,00 €
25 MG
470,00 €
About This Item
Fórmula empírica (notación de Hill):
C18H18N2O4S2
Número de CAS:
Peso molecular:
390.48
Código UNSPSC:
12352200
NACRES:
NA.77
128,00 €
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Ensayo
≥98% (HPLC)
Formulario
powder
color
white to light brown
solubilidad
DMSO: 10 mg/mL, clear
temp. de almacenamiento
2-8°C
cadena SMILES
[s]1c2c(c(c1NC(=S)NC(=O)c3ccccc3)C(=O)O)CC(OC2)(C)C
InChI
1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)
Clave InChI
ATSWBWHRHAQVFM-UHFFFAOYSA-N
Acciones bioquímicas o fisiológicas
CID 1067700 antagonizes ras-related protein Rab-7 and reduces class switch DNA recombination (CSR) in B cells and survival of plasma cells.[1]
CID 1067700 is a potent and competitive inhibitor of Ras-related GTPases that potently binds to Rab7 nucleotide binding site.
CID 1067700 is a potent and competitive inhibitor of Ras-related GTPases.
Características y beneficios
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Artículos
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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After resuspending 5 mg CID 1067700 in DMSO, should it still be stored at 4°C or should it be stored at -20°C?
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