SML0378

Ralfinamide mesylate

≥98% (HPLC)

• Sinónimos: (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate
• Fórmula empírica (notación de Hill): C₁₇H₁₉FN₂O₂ · CH₃SO₃H
• Número CAS: 202825-45-4
• Peso molecular: 398.45
• NACRES: NA.77
• PubChem Substance ID: 329825378
• UNSPSC Code: 12352200
• MDL number: MFCD19690932
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D 10 to 15° (c=1 HOAc)
• color: white to beige
• solubility: H₂O: >15 mg/mL
• storage temp.: 2-8°C
• SMILES string: CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
• InChI: 1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
• InChI key: CHQVNINIGBRKGZ-YDALLXLXSA-N

Descripción

Biochem/physiol Actions

Ralfinamide is a mixed sodium and N-type calcium channel blocker.

Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H301
• Indicaciones de precaución: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable