SML0360

TAK-715

≥98% (HPLC)

• Sinónimos: N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide
• Fórmula empírica (notación de Hill): C₂₄H₂₁N₃OS
• Número CAS: 303162-79-0
• Peso molecular: 399.51
• NACRES: NA.77
• PubChem Substance ID: 329825362
• UNSPSC Code: 12352200
• MDL number: MFCD17012805
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: faintly yellow to dark yellow
• solubility: DMSO: >15 mg/mL
• storage temp.: 2-8°C
• SMILES string: CCc1nc(-c2cccc(C)c2)c(s1)-c3ccnc(NC(=O)c4ccccc4)c3
• InChI: 1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)
• InChI key: HEKAIDKUDLCBRU-UHFFFAOYSA-N
• Gene Information: human ... MAPK14(1432)

Descripción

Biochem/physiol Actions

TAK-715 is a dual p38 MAPK and CKId/e inhibitor; inhibitor of Wnt-3a-stimulated β-catenin signaling.

TAK-715 is a potent p38 inhibitor that also inhibits CKId/e (casein kinase Id/e), known activator of Wnt/β-catenin signaling.

Features and Benefits

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H302,H319
• Indicaciones de precaución: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable