Documentos clave

Ver Toda la documentación

Saltar a

SML0057

Camostat mesylate

Name: Camostat mesylate
Brand: SIGMA
Price: 68.2 EUR

≥98% (HPLC), Serine protease inhibitor, powder

Oferta disponible

Sinónimos:

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate; FOY 305; FOY-S 980; Foipan mesylate

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas

Talla/SKU	Disponibilidad	Precio
10 mg	Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad	68,20 €
50 mg	Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad	254,00 €

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₂₀H₂₂N₄O₅·CH₃SO₃H

Número CAS:

59721-29-8

Peso molecular:

494.52

UNSPSC Code:

12352203

PubChem Substance ID:

329825123

NACRES:

NA.77

MDL number:

MFCD00941410

Assay:

≥98% (HPLC)

Form:

powder

68,20 €

Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad

Solicita un pedido personalizado

Servicio técnico

¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.

Permítanos ayudarle

Propiedades

Nombre del producto

Camostat mesylate, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

H₂O: ≥24 mg/mL

originator

Novartis

storage temp.

2-8°C

SMILES string

CS(O)(=O)=O.CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(N)=N)cc2)cc1

InChI

1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)

InChI key

FSEKIHNIDBATFG-UHFFFAOYSA-N

Descripción

Application

Camostat mesylate may be used in cell signaling studies.

Camostat mesylate has been used to determine the effect of transmembrane protease, serine (TMPRSS) family proteases on cell-cell fusion.

Biochem/physiol Actions

Camostat is a serine protease inhibitor, airway epithelial sodium channel (ENaC) attenuator.

Camostat is a synthetic, orally bioavailble serine protease inhibitor and airway epithelial sodium channel (ENaC) attenuator.

Camostat mesylate (CM) is used to treat pancreatitis and reflux esophagitis after gastrectomy.

Camostat mesylate inhibits the production of TNF-α and monocyte chemoattractant protein-1 (MCP-1) by monocytes. It also inhibits the activity of pancreatic stellate cells. Camostat mesylate regulates the cytokine expression and inflammation and is effective in the treatment of dibutyltin dichloride-induced rat pancreatic fibrosis.

Features and Benefits

This compound is featured on the Acid-Sensing (Proton-gated) Ion Channels (ASICs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 1

Este artículo	SML3997	N0289	SML3810
Sigma-Aldrich SML0057 Camostat mesylate	Sigma-Aldrich SML3997 FOY-251 mesylate	Sigma-Aldrich N0289 Nafamostat mesylate	Sigma-Aldrich SML3810 p-Nitrobenzyl mesylate
description ≥98% (HPLC)	description ≥98% (HPLC)	description ≥98% (HPLC)	description ≥98% (HPLC)
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. room temp	storage temp. -10 to -25°C
solubility H₂O: ≥24 mg/mL	solubility DMSO: 2 mg/mL, clear (warmed)	solubility H₂O: >10 mg/mL, DMSO: 10 mg/mL, clear	solubility DMSO: 2 mg/mL, clear
color white to tan	color white to beige	color white to beige	color white to beige