SML0043

Racecadotril

≥98% (HPLC)

• Sinónimos: (RS)-Benzyl N-[3-(acetylthio)-2-benzylpropanoyl]glycinate, (±)-Acetorphan, Acetorphan, Cadotril, Redotil, Tiorfan, Zedott
• Fórmula empírica (notación de Hill): C₂₁H₂₃NO₄S
• Número CAS: 81110-73-8
• Peso molecular: 385.48
• NACRES: NA.77
• PubChem Substance ID: 329825113
• UNSPSC Code: 12352200
• MDL number: MFCD00865520
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥44 mg/mL
• storage temp.: room temp
• SMILES string: CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2
• InChI: 1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)
• InChI key: ODUOJXZPIYUATO-UHFFFAOYSA-N

Descripción

Application

Racecadotril may be used to study enkephalinase-mediated cellular changes.

Biochem/physiol Actions

Neutral endopeptidase inhibitor; antidiarrheal

Racecadotril is a neutral endopeptidase inhibitor, an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

Inhibition of enkephalinase by Racecadotril prevents the breakdown of enkephalins in the gastrointestinal tract. This reduces secretion of water and electrolytes into the gut without affecting the mobility.

Features and Benefits

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS07,GHS09
• Palabra de advertencia: Warning
• Códigos de peligro: H302,H400
• Indicaciones de precaución: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable