SAB5701837

Anti-Phospho-POLR2A-S2 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: monoclonal
• Formulario: liquid
• reactividad de especies: human
• concentración: 0.75 mg/mL
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: P24928
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer2)
• Información sobre el gen: human ... POLR2A(5430)

Descripción

Descripción general

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

Inmunógeno

A phospho specific peptide corresponding to residues surrounding S2 of human POLR2A

Forma física

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable