SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Sinónimos: CVID6, S5.7, TAPA1, TSPAN28
• Código UNSPSC: 12352203

Propiedades

• conjugado: APC-Cy7 conjugate
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: M38, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: ( Human), rabbit, ( Cat)
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso UniProt: P60033
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD81(975)

Descripción

Descripción general

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Especificidad

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Inmunógeno

MOLT-4 (human T-ALL cell line)

Forma física

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparación

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Almacenamiento y estabilidad

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Otras notas

The antibody solution should be gently mixed before use.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable