Anti-Cofilin Antibody detects endogenous levels of total Cofilin protein.
Cofilin is a member of the actin depolymerizing factor/cofilin family. Among all members, cofilin‐1 is the predominant isoform. It is located on human chromosome 11q13.
Inmunógeno
The antiserum was produced against synthesized peptide derived from human Cofilin.
Immunogen Range: 61-110
Aplicación
Anti-Cofilin antibody has been used in western blotting.
Acciones bioquímicas o fisiológicas
Cofilin plays an important role in actin filament remodeling that is required in chemotaxis, cell migration and invasion of tumor cells.
Características y beneficios
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Forma física
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14
Gillett GT, et al.
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