SAB4300244

Anti-phospho-NFKB1 (pSer⁹²⁷) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-DKFZp686C01211 antibody produced in rabbit, Anti-EBP-1 antibody produced in rabbit, Anti-KBF1 antibody produced in rabbit, Anti-MGC54151 antibody produced in rabbit, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody produced in rabbit
• Número MDL: MFCD00802846
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: ~120 kDa; ~50 kDa
• reactividad de especies: rat, human, mouse
• concentración: 1 mg/mL
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (C-D-SP-G-V)
• Nº de acceso NCBI: NP_001158884.1
• Nº de acceso UniProt: P19838
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer927)
• Información sobre el gen: human ... NFKB1(4790)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of serine 927 (C-D-S(p)-G-V), according to the protein NFKB1.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descripción de destino

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable