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Merck

SAB4200713

Sigma-Aldrich

Anti-Human IgG (γ-chain specific) antibody, Mouse monoclonal

clone GG-5, purified from hybridoma cell culture

Sinónimos:

Mouse Anti-Human IgG (γ-chain specific)

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

forma del anticuerpo

purified from hybridoma cell culture

tipo de anticuerpo

primary antibodies

clon

GG-5, monoclonal

formulario

buffered aqueous solution

reactividad de especies

human

concentración

~1 mg/mL

técnicas

indirect ELISA: 0.25-0.5 μg/mL using 5μg/mL human IgG for coating

isotipo

IgG1

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Descripción general

Anti-Human IgG (γ-chain specific) antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GG-5 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with purified human IgG. Immunoglobulins (Igs) are produced by B lymphocytes and secreted into the plasma. Immunoglobulins can be divided into five main classes/isotypes which are IgA, IgD, IgE, IgG, and IgM. IgG class identity is determined by class-specific sequences in the Fc region of the heavy chain. IgG antibody class are the most abundant immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid and peritoneal fluid. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4). The IgG subclasses differ in their physical and chemical properties. Their distribution pattern is found to be age dependent and every subclass has a specific biological function.

Inmunógeno

purified human IgG

Aplicación

Anti-Human IgG (γ-chain specific) antibody, Mouse monoclonal has been used in indirect ELISA.

Acciones bioquímicas o fisiológicas

Immunoglobulins (Igs) serve as key players in the humoral immune response.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Structure and function of immunoglobulins.
Schroeder Jr H W and Cavacini L
The Journal of Allergy and Clinical Immunology, 125(2), S41-S52 (2010)
Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These

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