S3134
Streptokinase from β-hemolytic Streptococcus (Lancefield Group C)
lyophilized powder, ≥2,000 units/mg solid
Sinónimos:
Streptokinase from Streptococcus hemolyticus
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About This Item
Productos recomendados
formulario
lyophilized powder
actividad específica
≥2,000 units/mg solid
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
InChI
1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14)
Clave InChI
XRZWVSXEDRYQGC-UHFFFAOYSA-N
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Descripción general
Research area: Cell signaling
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.
Streptokinase is an extracellular enzyme produced by β-hemolytic Streptococcus. It is a single-chain polypeptide enzyme that consists of multiple structural domains, including α-, β-, and γ-domains.
Aplicación
Streptokinase has been used in a study to compare primary coronary intervention and thrombolytic therapy in myocardial infarction patients.
Streptokinase is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare.
Acciones bioquímicas o fisiológicas
Streptokinase is a potent plasminogen activator. Unlike human proteins tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), microbial streptokinase does not directly activate plasminogen. Instead, it activates plasminogen by fibrin-dependent and fibrin-independent. mechanisms. Streptokinase is effective in thrombolytic therapy. While streptokinase offers promising potential in treating ischemic stroke, its use also presents a significant risk of intracerebral hemorrhage. Streptokinase is also used in treating complicated parapneumonic effusions and empyema where allergic reactions, are rare.
Definición de unidad
One unit is equal to the amount of activity in one unit from a Streptokinase International Standard reference vial.
Forma física
Lyophilized powder containing ~50% total protein by biuret and sodium glutamate. Total protein composed of enzyme protein and human serum albumin.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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