P6902
Pheniramine maleate salt
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About This Item
Fórmula empírica (notación de Hill):
C16H20N2 · C4H4O4
Número de CAS:
Peso molecular:
356.42
Número CE:
Número MDL:
Código UNSPSC:
12352116
ID de la sustancia en PubChem:
NACRES:
NA.77
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Formulario
powder
cadena SMILES
OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccccc1)c2ccccn2
InChI
1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
Clave InChI
SSOXZAQUVINQSA-BTJKTKAUSA-N
Información sobre el gen
human ... HRH1(3269)
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Acciones bioquímicas o fisiológicas
Pheniramine maleate is a H1 histamine receptor antagonist. It is an alkylamine derivative. Structurally, pheniramine contains a chiral carbon atom with a hydrogen atom. Other substituents include the pyridyl, alkylamine and phenyl groups. It is used as an antiallergic drug for treating the common cold, respiratory allergies, urticaria, and systematic allergic reactions.
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We describe a young woman from a rural village in Nepal who suffered multiple wasp and hornet stings. She collapsed and was managed by a telephone consultation between a village health worker and a hospital specialist. The patient recovered fully.
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The aim of this study was to evaluate the local anesthetic effects of pheniramine and diphenhydramine, two histamine H₁ receptor antagonists, on spinal anesthesia and their comparison with lidocaine, a commonly used local anesthetic. After rats were injected intrathecally with
M R Louhaichi et al.
Talanta, 78(3), 991-997 (2009-03-10)
A new simple, rapid and sensitive liquid chromatographic method has been developed and validated for the simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold pharmaceuticals. The separation of these compounds was achieved within 13
Wenhua Gao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 904, 121-127 (2012-08-21)
A rapid and efficient dual preconcentration method of on-line single drop liquid-liquid-liquid microextraction (SD-LLLME) coupled to sweeping micellar electrokinetic chromatography (MEKC) was developed for trace analysis of three antihistamines (mizolastine, chlorpheniramine and pheniramine) in human urine. Three analytes were firstly
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