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Merck

MAK131

Sigma-Aldrich

Formaldehyde Assay

sufficient for 100 fluorometric tests

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1 KIT
423,00 €

423,00 €


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1 KIT
423,00 €

About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

423,00 €


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uso

sufficient for 100 fluorometric tests

método de detección

fluorometric

enfermedades relevantes

cancer

temp. de almacenamiento

2-8°C

Descripción general

Formaldehyde is widely employed in industry for a wide range of applications. It acts as a disinfectant and biocide, and is utilized as a tissue fixative and embalming agent.[1] Formaldehyde is a key metabolite produced during normal metabolism and contributes to methylation reactions and protein and nucleic acid synthesis. Increased production of formaldehyde has been observed in many cancer cell lines and increased formaldehyde concentration in urine has been associated with bladder and prostrate cancer.[2]

Aplicación


  • Modified Natural Rubber as a Simple Chemical Sensor with Smartphone Detection for Formaldehyde Content in a Seafood Sample.: This article explores the use of modified natural rubber as a chemical sensor, paired with smartphone detection, to measure formaldehyde content in seafood. This approach highlights the potential for accessible and mobile detection systems in food safety applications (Yeerum et al., 2022).

  • Optical enzymatic formaldehyde biosensor based on alcohol oxidase and pH-sensitive methacrylic-acrylic optode membrane.: The study develops an optical enzymatic biosensor for formaldehyde, using alcohol oxidase with a pH-sensitive membrane, offering a novel approach for quick and sensitive detection in various analytical applications (Nurlely et al., 2022).

Características y beneficios

Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.

Idoneidad

Suitable for the detection of formaldehyde in urine and other biological samples.

Principio

The Formaldehyde Assay kit provides a simple and direct procedure for measuring formaldehyde levels in urine and other biological samples. In this assay, formaldehyde is derivatized with acetoacetanilide in the presence of ammonia resulting in a fluorescent (λex = 370/λem = 470 nm) product, proportional to the formaldehyde present.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - STOT SE 1 - STOT SE 3

Órganos de actuación

Eyes,Central nervous system, Respiratory system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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Preguntas

1–2 de 2 Preguntas  
  1. Is the assay compatible with MES buffer? Is EDTA affecting the reaction?

    1 respuesta
    1. The principle of this kit is the reaction of formaldehyde with acetoacetanilide in the presence of ammonia. Neither a MESNA (4-Morpholineethanesulfonic acid, sodium) buffer nor EDTA in the test sample would be expected to interfere with this reaction. Having said that, it would be appropriate to run a blank containing MESNA and EDTA, and standards spiked with MESNA and EDTA, to confirm they they are not interfering with the test result...that is, making it either artificially high or low.

      ¿Le ha resultado útil?

  2. What is the limit of detection that the MAK131 Formaldehyde Assay is capable of?

    1 respuesta
    1. The kit is capable of detecting formaldehyde down to 1.5 micromolar or 45 ppb. The upper end of detection for undiluted samples is 100 micromolar, which is the highest concentration of the standard curve.

      ¿Le ha resultado útil?

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