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Merck

MAK106

Sigma-Aldrich

CETP Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Sinónimos:

Cholesteryl ester transfer protein activity assay kit

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About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 100 fluorometric tests

aplicaciones

pharmaceutical

método de detección

fluorometric

enfermedades relevantes

cardiovascular diseases

temp. de almacenamiento

2-8°C

Información sobre el gen

human ... CETP(1071)

Descripción general

Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP.

Aplicación

Cholesteryl ester transfer protein (CETP) activity Assay Kit has been used for measurement of CETP activity in the plasma samples.

Características y beneficios

Compatible with high-throughput handling systems.

Idoneidad

Suitable for the detection of cholesteryl ester transfer protein (CETP) in plasma / serum (fresh or frozen), recombinant or purified CETP.

Principio

The CETP Activity Assay Kit uses a proprietary substrate that enables the detection of CETP-mediated transfer of neutral lipid from the substrate to a physiological acceptor. The transfer activity results in an increase in fluorescence intensity (λEx=535 nm/λEm=587 nm). In a total volume of 200 μL, the assay is linear from 0.2 to 0.8 μL of normal human plasma. Assay results not affected by endogenous plasma HDL, LDL or VLDL concentrations.

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Código de clase de almacenamiento

10 - Combustible liquids


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