These 2 products are the same. LO4100 is the US version versus LO4200 is the International version.
LO4100
LOPAC®1280 - pequeña escala
Sinónimos:
Library of Pharmacologically Active Compounds - small scale
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UNSPSC Code:
12352200
EC Number:
200-664-3
NACRES:
NA.77
Form:
liquid
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liquid
Quality Segment
drug control
Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
shipped in
dry ice
storage temp.
−20°C
General description
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (25 μl at 10 mM in DMSO in archival storage racks).
LOPAC® 1280 is an extensively used library of pharmacologically active compounds. This library includes 1,280 marketed drugs, failed development candidates, and small molecules with well-characterized activities. LOPAC 1280 spans a broad molecular weight range, exhibits multiple mechanisms of action and interacts with a variety of biological receptors.[1]
Application
LOPAC® 1280 - Small Scale has been used:
- in sprouting assay to screen potential lymphangiogenic inhibitors and the signaling pathways involved in lymphangiogenesis[2][3]
- for identification of neuroactive compounds by measuring spontaneous activity within single zebrafish embryos by high-content screening assay[1]
- for high-throughput Screen for ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1; also known as CD39) and ecto-5′-nucleotidase (CD73) inhibitors[4]
Features and Benefits
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:
- Apoptosis
- G Proteins & Cyclic Nucleotides
- Gene Regulation & Expression
- Ion Channels
- Lipid Signaling
- Multi-Drug Resistance
- Neurotransmission
- Phosphorylation
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
Other Notes
For sale inside of the U.S. only. Customers outside the US should refer to Product Code LO4200.
Legal Information
LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2
Clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
188.6 °F
flash_point_c
87 °C
wgk
WGK 3
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What is the difference between the LOPAC1280 Products LO4100 and LO4200?
1 respuesta-
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Where can I find preparation instruction, storage and stability of the LOPAC 1280 - Small Scale Products LO4100 and LO4200?
1 respuesta-
The information is available in the datasheet of a similar product LO1280.
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What is the difference between the LOPAC®,1280 product numbers LO4100 and LO1280?
1 respuesta-
The compound per well in LO4100 is 25 ul at 10mM in DMSO versus 250 ul in the product LO1280
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Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200 US approved?
1 respuesta-
About 30% of the collection is made up of drugs approved for use in the US.
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Are the LOPAC 1280 - Small Scale Products LO4100 and LO4200 approved for therapeutic use?
1 respuesta-
Although there are FDA approved drugs in the set, we market them based on their research application and not necessarily their therapeutic indications. All of the information we have is included on the CD that is received with the library. We do not include information from the Physician's Desk Reference.
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What is the Department of Transportation shipping information for this product?
1 respuesta-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Can I get a list of CAS numbers of the drugs sent with LOPAC 1280 - Small Scale Products LO4100 and LO4200?
1 respuesta-
There is no CAS number list available.
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Is the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD shipped with the product?
1 respuesta-
Yes, the CD is shipped with the product. If you do not receive it you should contact Sigma-Aldrich Technical Services at techserv@sial.com or 1800-325-5832.
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What is on the LOPAC 1280 - Small Scale Products LO4100 and LO4200 CD?
1 respuesta-
The CD contains the SDFile - provided to construct a database containing structure, primary name, secondary, Pharmacological Activity. Product number and Rack position.
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