I8026
Anti-Interleukin-8 antibody produced in goat
affinity isolated antibody, lyophilized powder
Sinónimos:
Anti-CXCL8
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Seleccione un Tamaño
0.1 MG
278,50 €
278,50 €
Precio de catálogo557,00 €Ahorre 50 %Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Seleccione un Tamaño
Cambiar Vistas
0.1 MG
278,50 €
About This Item
278,50 €
Precio de catálogo557,00 €Ahorre 50 %Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Productos recomendados
origen biológico
goat
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
Formulario
lyophilized powder
reactividad de especies
human
técnicas
immunocytochemistry: 5-15 μg/mL
immunohistochemistry: 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
temp. de almacenamiento
−20°C
Información sobre el gen
human ... IL8(3576)
¿Está buscando productos similares? Visita Guía de comparación de productos
Descripción general
Interleukin 8 (IL-8) is an 8kD, 72 amino acid residue containing cytokine that belongs to C-X-C chemokine family . The IL-8 gene is mapped to human chromosome 4q13.3.
Especificidad
The antibody will neutralize the biological activity of recombinant and natural human IL-8, but not recombinant human GROα.
Inmunógeno
recombinant human IL-8 (CXCL8).
Aplicación
Anti-Interleukin-8 antibody can be used for the following :
- For neutralizing the biological activity of recombinant human IL-8 and natural human IL-8.
- Immunoblotting.
- ELISA.
Anti-Interleukin-8 antibody can be used in immunocytochemistry and immunohistochemistry.
Acciones bioquímicas o fisiológicas
Interleukin 8 (IL-8) stimulates neutrophils to produce lysosomal enzymes along with myeloperoxidase, α-mannosidase and β-glucuronidase . Goat anti-Interleukin-8 antibody reacts specifically with recombinant and natural human IL-8 but not with recombinant human GROα. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development. IL-8 is responsible for epithelial–mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis.
Forma física
Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
¿No encuentra el producto adecuado?
Pruebe nuestro Herramienta de selección de productos.
Código de clase de almacenamiento
13 - Non Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Identification and validation of vesicant therapeutic targets using a high-throughput siRNA screening approach.
Ruff A L, et al.
Archives of Toxicology, 90(2), 375-383 (2016)
Properties of pro-inflammatory cell type-specific leukocyte chemotactic cytokines, interleukin 8 (IL-8) and monocyte chemotactic and activating factor (MCAF).
N Mukaida et al.
Microbiology and immunology, 36(8), 773-789 (1992-01-01)
Elevated plasma il-8 concentration is related to severity of systemic inflammation in chronic spontaneous urticaria.
Kasperska-Zajac A, et al.
Journal of Biological Regulators and Homeostatic Agents, 31(4), 957-961 (2017)
T Yoshimura et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(24), 9233-9237 (1987-12-01)
Stimulated human monocytes release several proteins thought to play a role in inflammation, including interleukin 1, tumor necrosis factor, and plasminogen activator. We have purified another proinflammatory protein that is chemotactic for human neutrophils from conditioned medium of lipopolysaccharide-stimulated monocytes.
Sohlh2 suppresses epithelial to mesenchymal transition in breast cancer via downregulation of IL-8.
Ji S, et al.
Oncotarget, 7(31), 49411-49411 (2016)
Filtros activos
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico
