I5270

Anti-Interleukin-11 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• Sinónimos: Anti-IL-11
• Número MDL: MFCD00212981
• Código UNSPSC: 51111800
• NACRES: NA.41

Propiedades

• origen biológico: goat
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: lyophilized powder
• reactividad de especies: human
• técnicas: neutralization: suitable
• Nº de acceso UniProt: P20809
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... IL11(3589)

Descripción

Descripción general

Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation
Anti-Interleukin-11 antibody specifically reacts with human IL-11.

Especificidad

The antibody neutralizes the biological activity of recombinant human IL-11.

Inmunógeno

recombinant human IL-11 expressed in Sf 21 insect cells.

Aplicación

Anti-Human IL-11 is suitable for neutralization reactions.

Forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Nota de preparación

Purified using protein G.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)