I2526
Insulin-like Growth Factor-II human
≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Sinónimos:
IGF-II
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50 μG
422,00 €
422,00 €
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50 μG
422,00 €
About This Item
422,00 €
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Nombre del producto
Insulin-like Growth Factor-II human, IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
origen biológico
human
Nivel de calidad
recombinante
expressed in E. coli
Ensayo
≥98% (SDS-PAGE and HPLC)
Formulario
lyophilized powder
potencia
≤2.0 ng/mL ED50
calidad
endotoxin tested
mol peso
7.5 kDa
envase
pkg of 5X50 μg
pkg of 50 μg
técnicas
cell culture | mammalian: suitable
impurezas
≤0.1 EU/μg
Nº de acceso UniProt
temp. de almacenamiento
−20°C
Información sobre el gen
human ... IGF2(3481)
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Acciones bioquímicas o fisiológicas
IGF-II, also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. IGF-II binds to the IGF-II receptor, IGF-I receptor, and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-I receptor. However, during embryogenesis the roles of both IGF-II receptor and IR may be significant in promoting normal growth.
Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.
Forma física
Lyophilized from a 0.2 μm filtered solution with no additives.
Nota de análisis
The biological activity is measured by a cell proliferation assay using mouse FDC-P1
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Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Insulin-like Growth Factors (IGF)
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