This product is a whole antiserum. The antibody concentration varies from lot to lot and ranges from 3.0 - 5.0 mg/mL. This information is reported in the product Certificate of Analysis. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sigma/i1261#product-docuemntation
I1261
Anti-Human IgA (α-chain specific) antibody produced in goat
whole antiserum
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2 ML
128,00 €
128,00 €
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2 ML
128,00 €
About This Item
128,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Solicitar un pedido a granel
Productos recomendados
origen biológico
goat
conjugado
unconjugated
forma del anticuerpo
whole antiserum
tipo de anticuerpo
secondary antibodies
clon
polyclonal
contiene
15 mM sodium azide
técnicas
indirect ELISA: 1:50,000
quantitative precipitin assay: 3.0-5.0
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
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Descripción general
Immunoglobulin A (IgA) is found as two subclasses, that is, IgA1 and IgA2. IgA exists as a monomer or dimer in the secreted form. Dimeric IgA has a molecular weight of 390 kDa.
Especificidad
The antibody preparation is specific for human IgA when tested against purified human IgA, IgG, IgM, Bence Jones Kappa, and Bence Jones Lambda myeloma proteins
Aplicación
Anti-Human IgA (α-chain specific) antibody produced in goat has been used to determine the concentration of total IgA in serum samples by single radial immunodiffusion and enzyme-linked immunosorbent assay (ELISA).
Acciones bioquímicas o fisiológicas
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces.
In addition to passive immunity, IgA also induces active immunity by regulating the production of various chemokines and vital cytokines such as tumor necrosis factor (TNF) and interleukin (IL)-1β.
Forma física
Goat Anti-Human IgA is supplied as a liquid containing 0.1% sodium azide as preservative.
Almacenamiento y estabilidad
For continuous use, store at 2-8 °C for a maximum of one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
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There is still considerable controversy in the literature regarding the capacity of intramuscular messenger RNA (mRNA) vaccination to induce a mucosal immune response. To compare serum and salivary IgG and IgA levels among mRNA-vaccinated individuals with or without previous SARS-CoV-2
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Good morning, would you please provide me with an info about the precise concentration of substance I1261? Thank you in advane provide
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