HT5011

Disolución de formalina, tamponada neutra, 10%

case of 48 × 15 mL, histological tissue fixative

• Sinónimos: Formaldehyde, Methanal
• Número MDL: MFCD00003274
• Código UNSPSC: 12352114
• ID de la sustancia en PubChem: 24895886
• NACRES: NA.47

Propiedades

• envase: case of 48 × 15 mL
• concentración: 10% formalin (approx. 4% formaldehyde)
• color: colorless
• pH: 6.90-7.10
• densidad: 1.080 g/cm³
• aplicaciones: hematology; histology
• temp. de almacenamiento: room temp
• cadena SMILES: [O-]#[C+H2]
• InChI: 1S/CH2O/c1-2/h1H2
• Clave InChI: WSFSSNUMVMOOMR-UHFFFAOYSA-N

Descripción

Descripción general

Formaldehyde is both a non-coagulant and an additive fixative. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Once properly fixed, the tissue should be able to withstand the subsequent stages of tissue processing or staining. Although there is no true universal fixative, 10% neutral buffered formalin (NBF) is perhaps the most commonly used fixative throughout the world for light microscopy and is a somewhat forgiving fixative. Of the dozens and dozens of available fixatives, it is hard to imagine a fixative more commonly used than 10% NBF. 10% neutral buffered formalin is well suited for large throughput laboratories, and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue.

Aplicación

10% neutral buffered formalin (NBF) is a popular general purpose histological fixative. It has been used to fix tissues, protein complexes and tumor samples.

Propósito general popular, fijador histológico.

Envase

Case containers are polypropylene with white leak-proof lids and are partially prefilled with 10% NBF.

Forma física

Disolución tamponada neutra

Almacenamiento y estabilidad

Store tightly closed at room temperature. Do not freeze.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302 + H332,H317,H341,H350
• Consejos de prudencia: P202 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 185.0 °F
• Punto de inflamabilidad (°C): 85 °C
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter