H4036

L-histidina monohydrochloride monohydrate

• Sinónimos: Ácido Lα-amino-β-(4-imidazolil) propiónico monohydrochloride
• Fórmula empírica (notación de Hill): C₆H₉N₃O₂ · HCl · H₂O
• Número CAS: 5934-29-2
• Peso molecular: 209.63
• UNSPSC Code: 12352209
• NACRES: NA.26
• eCl@ss: 32160406
• MDL number: MFCD00151027
• Beilstein/REAXYS Number: 4168261

Propiedades

• biological source: non-animal source
• Quality Segment: 400
• assay: ≥98.5%
• form: powder
• manufacturer/tradename: Ajinomoto
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, heavy metals, residual solvents, tested
• mp: 254 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): downstream processes; pharma/biopharma processes; pharmaceutical (small molecule)
• foreign activity: cytotoxicity, tested
• SMILES string: O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
• InChI key: CMXXUDSWGMGYLZ-XRIGFGBMSA-N

Descripción

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Histidine, an essential amino acid. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Histidine monohydrochloride monohydrate is a modified version of L-Histidine with improved solubility.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 1
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)