G5419

Anti-GAD1/GAD2 Antibody

mouse monoclonal, K-87

• Sinónimos: Anti-GAD 67
• Número MDL: MFCD06202147
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• Nombre del producto: Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse, clone K-87, purified antibody
• origen biológico: mouse
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: K-87, monoclonal
• mol peso: antigen 67 kDa
• reactividad de especies: rat, mouse, human
• concentración: ~1 mg/mL
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step); western blot: 1:500-1:20,000 using mouse brain extract
• isotipo: IgG1κ
• Nº de acceso UniProt: Q99259
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GAD1(2571) ; mouse ... Gad1(14415) ; rat ... Gad1(24379)

Descripción

Descripción general

Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.

Especificidad

Reacts specifically with GAD67. Does not crossreact with GAD65.

Inmunógeno

This peptide does not share homology with GAD65.

synthetic peptide from mouse GAD67 (amino acids 87-106).

Aplicación

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).

Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:

• immunohistofluorescence[1]
• western blotting
• immunohistochemistry[2].

Acciones bioquímicas o fisiológicas

Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.

Forma física

Solution in phosphate buffered saline containing 0.01% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)