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G5009

Sigma-Aldrich

γ-Globulins from bovine blood

≥99% (agarose gel electrophoresis)

Sinónimos:

Bovine γ-Globulin

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1 G
63,20 €
5 G
220,00 €
10 G
491,00 €
25 G
841,00 €
100 G
2910,00 €

63,20 €


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1 G
63,20 €
5 G
220,00 €
10 G
491,00 €
25 G
841,00 €
100 G
2910,00 €

About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.61

63,20 €


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origen biológico

bovine blood

Nivel de calidad

Ensayo

≥99% (agarose gel electrophoresis)

Formulario

powder

composición

NaCl, ≤4%

técnicas

enzyme immunoassay: suitable

solubilidad

0.9% NaCl: soluble 25 mg/mL

temp. de almacenamiento

−20°C

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Descripción general

Bovine gamma globulin (BGG) is an important component of the immune system of cows and other bovines. BGG is found in the blood of bovines and is primarily used in the production of medical products such as vaccines, serums, and diagnostic reagents. BGG can also be used to treat certain medical conditions, such as hepatitis B, as well as to boost immunity in humans and other animals.

Aplicación

Bovine γ-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution which affect the biological properties of artificial articular joints.[1] It is also used to determine immunoglobulin G in bovine colostrum and milk using direct biosensor SPR-immunoassay.[2]
Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.

Acciones bioquímicas o fisiológicas

The γ-G globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow γ-G globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine γ-A was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.[3]

Nota de preparación

Prepared from Cohn Fraction II, III

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Rui Fang et al.
eLife, 11 (2022-01-21)
The ring-like ATPase complexes in the AAA+ family perform diverse cellular functions that require coordination between the conformational transitions of their individual ATPase subunits (Erzberger and Berger, 2006; Puchades et al., 2020). How the energy from ATP hydrolysis is captured
Marc-Olivier Montjovent et al.
Bioanalysis, 9(18), 1385-1393 (2017-09-29)
Recombinant glycoprotein produced in nonhuman mammalian cell lines can be modified with the immunogenic nonhuman sialic N-glycolylneuraminic acid (Neu5Gc). We describe here a validated method for detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes. An electrochemiluminescent method
Harvey E Indyk et al.
Journal of AOAC International, 86(2), 386-393 (2003-05-02)
An automated biosensor surface-plasmon resonance-based assay was developed for the determination of immunoglobulin G (IgG) in bovine milk and colostrum with either goat or rabbit antibovine IgG or protein G used as detecting molecule. The method is configured as a
T Kitano et al.
Journal of biomechanics, 34(8), 1031-1037 (2001-07-13)
The relationship between the coefficient of friction and pH value or protein constituents of lubricating fluid, together with viscosity, were studied within a bearing surface model for artificial joint, ultra-high molecular weight polyethylene (UHMWPE) against stainless steel (SUS), using a
Zijing Chen et al.
Genetics, 215(3), 713-728 (2020-05-22)
TRP channels function in many types of sensory receptor cells. Despite extensive analyses, an open question is whether there exists a family of auxiliary subunits, which could influence localization, trafficking, and function of TRP channels. Here, using Drosophila melanogaster, we

Preguntas

1–5 de 5 Preguntas  
  1. Sehr geehrte Damen und Herren, wir würden gern die Verpackungsgröße 100g, γ-Globuline aus Rinderblut (CAS-Nummer: 9007-83-4) bei ihnen bestellen. Können sie uns zufällig sagen wie groß die Verpackungsmaße dieses Gebindes ist? Vielen Dank & viele Grüße

    1 respuesta
    1. The 100G quantity of this product is packaged in a 5 liter white HDPE screw cap bottle. The dimensions are as follows:
      Volume - 5000 ml
      Length - 168 ± 2 mm
      Width - 168 ± 2 mm
      Height - 310 ± 3 mm

      ¿Le ha resultado útil?

  2. Is the product G5009 composed of a mixture of immunoglobulin isotypes, or does it contain only the IgG isotype?

    1 respuesta
    1. G5009 gamma-globulin is a mixture of IgG, IgM, and IgA.

      ¿Le ha resultado útil?

  3. What is the class of immunoglobulins in Product G5009, γ-Globulins from bovine blood?

    1 respuesta
    1. The gamma-globulin is a mixture of IgG (80%), IgM (10%), and IgA (<10%).

      ¿Le ha resultado útil?

  4. What is the Department of Transportation shipping information for this product?

    1 respuesta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      ¿Le ha resultado útil?

  5. What is the molecular weight of Product G5009, γ-Globulins from bovine blood?

    1 respuesta
    1. The molecular weight of 150,000 is based on 2 heavy chains (55,000 each) and 2 light chains (20,000 each).

      ¿Le ha resultado útil?

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