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Merck

FD70S

Sigma-Aldrich

Isotiocianato de fluoresceína-dextrano

average mol wt 60,000-76,000

Sinónimos:

FITC–Dextrano

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100 MG
81,90 €
250 MG
139,00 €
1 G
435,00 €
5 G
1162,00 €

81,90 €


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100 MG
81,90 €
250 MG
139,00 €
1 G
435,00 €
5 G
1162,00 €

About This Item

Número de CAS:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.25

81,90 €


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origen biológico

bacterial (Leuconostoc mesenteroides)

conjugado

FITC conjugate

Formulario

powder

mol peso

average mol wt 60,000-76,000

Extensión del etiquetado

0.003-0.020 mol FITC per mol glucose

color

yellow to yellow-orange

solubilidad

H2O: 25 mg/mL, clear to slightly hazy, yellow-orange

temp. de almacenamiento

2-8°C

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Aplicación

Dextrano marcado con isotiocianato de fluoresceína para su posible uso en estudios de perfusión en animales.
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.[1] Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability.[2] FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.[3]

Ligadura / enlace

Similar to FD-70, but produced by Sigma.

Otras notas

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Maira Carrillo et al.
Medicine, 97(39), e12392-e12392 (2018-10-04)
Imaging of placental tissues is a difficult task, because of specific for this organ complex multicellular and 3D tissue structure. The tissue clearing systems (X-CLARITY) system is a valuable tool for the examining the expression of molecular pathways in whole
Gabriela Hurtado-Alvarado et al.
PloS one, 11(11), e0167236-e0167236 (2016-11-29)
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory mediators in rodents. Those inflammatory mediators may modulate the blood-brain barrier and constitute a link between sleep loss and blood-brain barrier physiology. We propose that adenosine action on its A2A
Haruo Aramoto et al.
American journal of physiology. Heart and circulatory physiology, 287(4), H1590-H1598 (2004-05-25)
Vascular endothelial growth factor (VEGF) induces mild vasodilation and strong increases in microvascular permeability. Using intravital microscopy and digital integrated optical intensity image analysis, we tested, in the hamster cheek pouch microcirculation, the hypothesis that differential signaling pathways in arterioles
Ting Su et al.
International journal of pharmaceutics, 555, 291-302 (2018-11-25)
Polyphosphates are important polyanionic electrolytes that play a major role in stabilization and consolidation of colloids surface and interior microstructures. In this study, the polyelectrolyte complexes (PEC) microcapsules (sodium cellulose sulfate-chitosan hydrochloride, sample 1), and the patched ones via sodium
Chen-Mei Chen et al.
International journal of molecular sciences, 21(10) (2020-05-18)
Zinc oxide nanoparticles (ZnONPs) are frequently encountered nanomaterials in our daily lives. Despite the benefits of ZnONPs in a variety of applications, many studies have shown potential health hazards of exposure to ZnONPs. We have shown that oropharyngeal aspiration of

Contenido relacionado

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Preguntas

1–2 de 2 Preguntas  
  1. Is this dextran lysine-fixable?

    1 respuesta
    1. This product is not considered lysine-fixable. The material would have to be chemically treated in order to be suitable. Typically, dextrans used to prepare lysine-fixable products are anionic (see product 90718). Should it be of interest, product B9139 is a Biotin-dextran, lysine-fixable product option. See the link below to review this product page:
      https://www.sigmaaldrich.com/product/sigma/b9139

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  2. How long would a diluted stock (i.e. 5 mg/mL) be stable for at 4C?

    1 respuesta
    1. The long term solution stability of this product has not been determined. Solutions should be protected from light. Per literature references, FITC-Dextran is stable in vivo for more than 24 hours. Please see the link below for additional information.
      https://www.sigmaaldrich.com/technical-documents/technical-article/cell-culture-and-cell-culture-analysis/cell-based-assays/fluorescein-isothiocyanate-dextran

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