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E4250

(−)-Epinephrine

≥99% (HPLC), powder, adrenoceptor agonist

Sinónimos:

(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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Talla/SKUDisponibilidadPrecio
1 g
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39,90 €
5 g
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152,00 €
10 g
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237,00 €

Acerca de este artículo

Fórmula lineal:
(HO)2C6H3CH(OH)CH2NHCH3
Número CAS:
Peso molecular:
183.20
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-098-7
MDL number:
Beilstein/REAXYS Number:
2368277

39,90 €


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Nombre del producto

(−)-Epinephrine,

Quality Segment

mp

215 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

Biochem/physiol Actions

Adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

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Este artículo
PHR8531E4375P8155
Epinephrine pkg of 400 mg, certified reference material, pharmaceutical secondary standard

PHR8531

Epinephrine

description

-

description

pkg of 400 mg, certified reference material, pharmaceutical secondary standard

description

solid

description

analytical standard

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

-

mp

215 °C (dec.) (lit.)

mp

215 °C (dec.) (lit.)

mp

-

mp

143-145 °C (lit.)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)
rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)

Gene Information

-

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)


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pictograms

Skull and crossbones

signalword

Danger

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Oral



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Preguntas

1–2 de 2 Preguntas  
  1. When this product is reconstituted in DMSO, at what temperature should it be stored?

    1 respuesta
    1. The stability of this product when prepared in DMSO has not been determined. In general, solutions in DMSO should be prepared fresh and used promptly. Epinephrine is most stable in acidic aqueous solutions at pH 3.6, when stored tightly sealed under nitrogen or argon. Solutions prepared in basic buffers are unstable and turn red in color due to degradation. Published literature indicates solutions are stable for at least 1 month when stored at 4°C or 25°C. Commercial solutions are often assigned a shelf life of greater than 1 year.

      ¿Le ha resultado útil?

  2. Hi, Is it possible to reconstitute the epinephrine solution in something less aggressive than 0.5 M HCl ? Sincerely, Alex

    1 respuesta
    1. This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

      ¿Le ha resultado útil?

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