immunohistochemistry: suitable indirect ELISA: suitable western blot: 0.25-0.5 μg/mL using recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267)
The signalling by dEGFR (also known as Torpedo or DER) is crucial for the development processes in Drosophila. The dEGFR signalling results in the activation of the canonical RAS/RAF/MEK/MAPK cascade. A variety of modulators such as Gro, TGF-α, Argos, Sprouty and Notch play an integrative role in EGFR signalling. The other pathways EGFR is involved in the development of the compound eye, larval, eye, wing and malphigian tubule development. Monoclonal Anti-dEGFR, Cytoplasmic Domain recognizes Drosophila Epidermal Growth Factor Receptor (EGFR). The antibody epitope resides within amino acids 1200-1267 of Drosophila EGFR.
Inmunógeno
recombinant cytoplasmic domain fragment of the Drosophila EGFR (amino acids 1200-1267).
Aplicación
Anti-dEGF Receptor, Cytoplasmic Domain antibody may be used for immunoblotting at a working concentration of 0.25-0.5 μg/ml. The antibody is suitable for immunohistochemistry and ELISA.
Forma física
Solution in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
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