D7003
DL-Dihydroorotic acid
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C5H6N2O4
Número CAS:
Peso molecular:
158.11
UNSPSC Code:
12352204
PubChem Substance ID:
MDL number:
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powder
SMILES string
OC(=O)C1CC(=O)NC(=O)N1
InChI
1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)
InChI key
UFIVEPVSAGBUSI-UHFFFAOYSA-N
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Timo Heikkilä et al.
Journal of medicinal chemistry, 50(2), 186-191 (2007-01-19)
Pyrimidine biosynthesis presents an attractive drug target in malaria parasites due to the absence of a pyrimidine salvage pathway. A set of compounds designed to inhibit the Plasmodium falciparum pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (PfDHODH) was synthesized. PfDHODH-specific inhibitors with
Ceyhun Bereketoglu et al.
Physiological genomics, 49(10), 549-566 (2017-09-10)
Bioaccumulative environmental estrogen, nonylphenol (NP; 4-nonylphenol), is widely used as a nonionic surfactant and can affect human health. Since genomes of
Joana Costeira-Paulo et al.
Cell chemical biology, 25(3), 309-317 (2018-01-24)
The interactions between proteins and biological membranes are important for drug development, but remain notoriously refractory to structural investigation. We combine non-denaturing mass spectrometry (MS) with molecular dynamics (MD) simulations to unravel the connections among co-factor, lipid, and inhibitor binding
Al-Walid A Mohsen et al.
Biochemistry, 43(21), 6498-6510 (2004-05-26)
Dihydroorotate dehydrogenase B (DHODB) is a complex iron-sulfur flavoprotein that catalyzes the conversion of dihydroorotate to orotate and the reduction of NAD(+). The enzyme is a dimer of heterodimers containing an FMN, an FAD, and a 2Fe-2S center. UV-visible, EPR
Danny T Huang et al.
Biochemistry, 45(27), 8275-8283 (2006-07-06)
Dihydroorotase (DHOase, EC 3.5.2.3) from the extreme thermophile Bacillus caldolyticus has been subcloned, sequenced, expressed, and purified as a monomer. The catalytic properties of this thermophilic DHOase have been compared with another type I enzyme, the DHOase domain from hamster
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| D7003-100MG | 04061832407746 |
| D7003-1G | 04061826016312 |
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