The concentration is expressed as weight/volume (w/v). The exact concentration is provided on the lot-specific certificate of analysis (COA).
C9394
Chlorhexidine digluconate solution
20% in H2O
Sinónimos:
Bis(p-chlorophenyl)diguanidohexane digluconate, 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
25 mL | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 106,00 € |
100 mL | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 310,00 € |
500 mL | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 885,00 € |
Acerca de este artículo
Número CAS:
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
MDL number:
106,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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liquid
Quality Segment
concentration
20% in H2O
solubility
water: soluble 50 % (w/v)
density
1.06 g/mL at 25 °C (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
InChI
1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1
InChI key
YZIYKJHYYHPJIB-UUPCJSQJSA-N
Application
Chlorhexidine has been used to study how essential oils improve skin antisepsis when combined with chlorhexidine digluconate and is used for skin permeation studies . Chronic rinsing with chlorhexidine has been shown to decrease the saltiness of NaCl and the bitterness of quinine.
Used to study mechanism of membrane dysruption by bis(biguanide) molecules.
Biochem/physiol Actions
Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Light sensitive.
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Este artículo | |||
|---|---|---|---|
| description 20% in H2O | description Pharmaceutical Secondary Standard; Certified Reference Material | description ≥98% | description European Pharmacopoeia (EP) Reference Standard |
| mode of action cell membrane | interferes | mode of action - | mode of action - | mode of action - |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level 300 | Quality Level 100 | Quality Level - |
| form liquid | form - | form powder | form - |
| solubility water: soluble 50 % (w/v) | solubility - | solubility - | solubility - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
Palabra de advertencia
Danger
Códigos de peligro
Indicaciones de precaución
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
Clase de almacenamiento
12 - Non Combustible Liquids
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
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Is the 20% chlorhexidine digluconate (C9394) calculated as weight/weight (w/w) or weight/volume (w/v)? Because the specific gravity is given as 1.06 g/mL, this matters for calculating the molar concentration.
1 respuesta-
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How can I determine the shelf life / expiration / retest date of this product?
1 respuesta-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf¿Le ha resultado útil?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 respuesta-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Hi, Is this pharma grade ? Kidn regards Archana
1 respuesta-
No, this product is not pharmaceutical grade. It is intended for research use only. Currently, a pharmaceutical grade of this material is not available.
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