C6491

Chrysomycin B

≥98% (HPLC), solid

• Fórmula empírica (notación de Hill): C₂₇H₂₈O₉
• Número CAS: 83852-56-6
• Peso molecular: 496.51
• NACRES: NA.77
• PubChem Substance ID: 24892870
• UNSPSC Code: 12352200
• MDL number: MFCD07370132

Propiedades

• assay: ≥98% (HPLC)
• form: solid
• solubility: DMF: soluble, DMSO: soluble, ethanol: moderately soluble, methanol: moderately soluble
• antibiotic activity spectrum: neoplastics
• mode of action: enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: COc1cc(C)cc2C(=O)Oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@](C)(O)[C@H]5O)c34)-c12
• InChI: 1S/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1
• InChI key: BJPYMDSMDBCKEP-QSMCFSHASA-N

Descripción

Biochem/physiol Actions

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II.

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II. Exhibits antitumor activity against human cell lines K562, HT29, MCF7, PC6, and MKN28.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)