C4011
Cytochrome c from pigeon breast muscle
≥95% based on Mol. Wt. 12,173 basis
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| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
25 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 587,00 € 498,95 € |
Acerca de este artículo
Form:
powder
Assay:
≥95% based on Mol. Wt. 12,173 basis
Biological source:
pigeon muscle (breast)
498,95 €
Precio de catálogo587,00 €Ahorre 15 %Promoción solo por Internet
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarlebiological source
pigeon muscle (breast)
Quality Segment
assay
≥95% based on Mol. Wt. 12,173 basis
form
powder
technique(s)
cell culture | mammalian: suitable
storage temp.
−20°C
Application
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.
Biochem/physiol Actions
The ready fluctuation of cytochrome c within the cell between ferrous and ferric states, makes it an efficient biological electron-transporter. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal catalyst of respiration, it forms the essential electron-bridge between the respirable substrates and oxygen.
Preparation Note
Prepared with acetic acid without using TCA.
Other Notes
View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enzymeexplorer.
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Este artículo | |||
|---|---|---|---|
| biological source pigeon muscle (breast) | biological source horse heart | biological source horse heart | biological source Saccharomyces cerevisiae |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell based assay: suitable | technique(s) cell based assay: suitable |
| assay ≥95% based on Mol. Wt. 12,173 basis | assay ≥95% (SDS-PAGE), ≥95% based on Mol. Wt. 12,384 basis | assay ≥95% (SDS-PAGE) | assay ≥85% based on Mol. Wt. 12,588 basis |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level 200 |
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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